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Sirena Gulamgaus was born in Toronto, Canada. She is the sister of actor Noorin Gulamgaus. Sirena gained interest in acting at the age of 6, after watching her brother perform on the stage. Sirena started off by acquiring a recurring role on the final season of Orphan Black, acting opposite Tatiana Maslany. Afterwards, she was cast as a series regular on the CTV and NBC series Transplant. Following the first season of Transplant, Sirena was cast as a series regular on the MGM+ series Chapelwaite, opposite Adrien Brody. With the success of these series, Sirena quickly built a name for herself in the industry. She can next be seen as the lead in the Netflix film, Code 8 Part II. And also, in a supporting role in Caitlin Cronenberg's directorial debut; Humane.